Challenge ResultsΒΆ

Thank you to everyone who participated in the AI4Life Calcium Imaging Denoising Challenge 2025 (AI4Life-CIDC25).

This challenge focused on unsupervised denoising of calcium imaging microscopy data. Calcium imaging data are spatially and temporally structured, so denoising methods need to preserve both image content and temporal activity dynamics.

The results below summarise the best published submissions for each leaderboard. The official ranking score is stSNR, the spatio-temporal signal-to-noise ratio, averaged across the files in each leaderboard dataset.

Only the best published result for each participant is listed, showing the top-3 scoring algorithms for each leaderboard.


Final Submission Phase: Content GeneralisationΒΆ

Rank Name Affiliation Algorithm Result stSNR Link to code
1 edoardogiacomello Human Technopole N2V 3D 22.14 GitHub
2 chhayanshporwal Rajasthan Technical University Kota Noise2Void 3D 21.18 GitHub
3 aagamsheth Ahmedabad University 3D N2V U Net DVT Inspired 20.85 GitHub

Final Submission Phase: Noise Level GeneralisationΒΆ

Rank Name Affiliation Algorithm Result stSNR Link to code
1 edoardogiacomello Human Technopole N2V 3D 16.75 GitHub
2 chhayanshporwal Rajasthan Technical University Kota Noise2Void 3D 15.59 GitHub
3 mcroft Human Technopole Noise2Noise 2D Windowed 15.10